Spatial resolution limits for synchrotron-based spectromicroscopy in the mid- and near-infrared

Spatial resolution limits for synchrotron-based spectromicroscopy in the mid- and near-infrared.

Spatial resolution tests were performed on beamline 1.4.4 at the Advanced Light Source in Berkeley, CA, USA, a third-generation synchrotron light source. This beamline couples the high-brightness synchrotron source to a Thermo-Electron Continumicrom XL infrared microscope. Two types of resolution tests were performed in both the mid-IR and near-IR. The results are compared with a diffraction-li...

Spatial resolution limits for synchrotron-based infrared spectromicroscopy

Detailed spatial resolution tests were performed on beamline 1.4.4 at the Advanced Light Source synchrotron facility in Berkeley, CA. The high-brightness synchrotron source is coupled at this beamline to a Thermo-Electron ContinulmXL infrared microscope. Two types of resolution tests in both the mid-IR (using a KBr beamsplitter and an MCT-A* detector) and in the near-IR (using a CaF2 beamsplitt...

Fundamental Limits of Detection in the Near and Mid Infrared

Biomolecular diagnosis of human glioblastoma multiforme using Synchrotron mid-infrared spectromicroscopy.

Glioblastoma multiforme (GBM) is one of the most malignant human tumors, with a uniformly poor outcome. One obstacle in curing malignant brain tumors is the limitation of conventional light microscopy in detecting microscopic residual tumor in biopsy samples from the perimeter of the surgically resected tumor. We further refined the identification of GBM tumor tissue at the sub-cellular level, ...

Spatial resolution bias in the mid - infrared Starburst / AGN classification

We present the effects of limited spatial resolution to the observed mid-infrared (MIR) spectrum of an active galactic nucleus (AGN) surrounded by a disk with massive star forming regions. Using MIR observations of the face-on nearby Seyfert 1 galaxy NGC 6814, we vary the observing aperture and examine the evolution of the observed AGN/starburst fraction with our MIR diagnostic. We show that th...